March-April 2018| Vol 1| Issue 2
Molecular mechanisms involved in angiogenesis and potential target of antiangiogenesis in human glioblastomas
Glioblastoma multiforme (GBM) is the most devastating and common primary malignant brain tumor in adults. Angiogenesis as a hallmark in glioblastoma has attracted more and more attention of the resear...
Angiogenesis in glioma
Despite aggressive surgery, radiotherapy, and chemotherapy, malignant gliomas remain uniformly fatal. To progress, these tumors stimulate the formation of new blood vessels through processes driven pr...
Correlation of conventional magnetic resonance imaging features with O6-methylguanine-DNA-methyltransferase gene promoter methylation status and survival outcomes in patients with newly diagnosed glioblastoma: Single-center correlative imaging substudy from a prospective clinical trial
Background: Imaging features may be reflective of inherent disease biology and serve as potentially useful biomarkers in primary brain tumors. This study aimed to correlate conventional magneti...
The delta-like ligand 4-notch signaling inhibits tumor angiogenesis but promotes tumor growth in primary glioblastoma: An immunohistochemical study
Background: Delta-like ligand 4 (DLL4) is a key Notch ligand implicated in tumor angiogenesis. However, previous studies have shown that the DLL4-Notch signaling inhibits tumor angiogenesis but...
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Reprogramming glioma cell cultures with retinoic acid: Additional arguments for reappraising the potential of retinoic acid in the context of personalized glioma therapy
Background: Glioma, notably glioblastoma multiforme, is characterized by extensive inter-and intra-tumoral heterogeneity. Surprisingly, the potential for differentiation of glioma cells has not...
Glioma, a publication of Chinese Society of Neuro-Oncology (CSNO), is a peer-reviewed print + online Bimonthly journal.
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