April-June 2019| Vol 2| Issue 2
Tumor treating fields therapy for glioblastoma: An update
Tumor treating fields are alternating electric fields that have a therapeutic effect on newly diagnosed and recurrent glioblastomas. The fields act on cellular proteins with large dipole moment that a...
A multifaceted review of temozolomide resistance mechanisms in glioblastoma beyond O-6-methylguanine-DNA methyltransferase
Temozolomide (TMZ), an oral alkylating agent, is a cornerstone of standard-of-care multimodality therapy for glioblastoma. In spite of significant efforts to treat this disease, the tumor carries a po...
MicroRNA-based chemoresistance in glioblastoma
Glioblastoma (GBM) is the most common malignant tumor of the central nervous system in adults. GBM is characterized by violent invasion and poor prognosis. Commonly, there are three main conventional ...
Chimeric antigen receptor T-cells for glioblastoma: The journey ahead
Chimeric antigen receptors (CARs) are genetically engineered transmembrane cell receptors consisting of an antigen-binding ectodomain fused to an activating intracellular T-cell signaling chain. Graft...
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Real-world management and survival outcomes of patients with newly diagnosed gliomas from a single institution in China: A retrospective cohort study
Background and Aim: Guidelines recommend adjuvant treatment for patients with high-grade gliomas and low-grade gliomas with high risk of progression. In clinical practice, however, treatments m...
Glioma, a publication of Chinese Society of Neuro-Oncology (CSNO), is a peer-reviewed print + online Quarterly journal.
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