January-March 2022| Vol 5| Issue 1
New changes in pathological diagnosis of brain tumors in the modern molecular era
Since 2016, the pathological diagnosis of tumors of the central nervous system (CNS) has undergone great changes, owing to the introduction of molecular pathological techniques and molecular genetic...
The diverse landscape of histone-mutant pediatric high-grade gliomas: A narrative review
Pediatric high-grade gliomas (pHGGs) are the leading cause of tumor-related death in children, with diffuse midline gliomas representing the worst prognoses. Despite decades of clinical trials, no e...
Glioma stem cells and their microenvironment: A narrative review on docking and transformation
Significant new progress was made 10 years ago in the hypothesis that neuroglial cells, neural stem cells, and glioma stem cells (GSCs) depend on the tumor microenvironment (TME) transformation: (1)...
A novel nomogram based on DNA damage response-related gene expression in patients with O-6-methylguanine-DNA methyltransferase unmethylated glioblastoma receiving temozolomide chemotherapy: A population-based analysis
Background and Aim: Glioblastoma (GBM) is the most lethal primary brain tumor. Patients with unmethylated O-6-methylguanine-DNA methyltransferase (MGMT) promoter have higher MGM...
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Initial report of a clinical trial evaluating the safety and efficiency of neoadjuvant camrelizumab and apatinib in patients with recurrent high-grade gliomas: A prospective, phase II, single-arm study
Background and Aim: High-grade glioma is the most common malignant primary brain tumor in the central nervous system. Multiple strategies such as surgery, radiotherapy, and chem...
Glioma, a publication of Chinese Society of Neuro-Oncology (CSNO), is a peer-reviewed print + online Quarterly journal.
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