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Year : 2021  |  Volume : 4  |  Issue : 3  |  Page : 54-56

Diagnostic challenges in epithelioid glioblastoma of the cerebellum: A case report

1 Department of Pathology, Government Medical College and Hospital, Chandigarh, India
2 Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
3 Department of Neurosurgery, Government Medical College and Hospital, Chandigarh, India

Correspondence Address:
Dr. Phiza Aggarwal
Department of Pathology, Government Medical College and Hospital, Sector-32, Chandigarh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/glioma.glioma_13_21

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Epithelioid glioblastoma (eGB) is an uncommon morphological variant of isocitrate dehydrogenase wild-type GB that commonly presents as a cerebral mass in young adults and children. Here, we report the case of a 22-year-old man who presented with a cerebellar tumor. With the provisional diagnosis of pilocytic astrocytoma and adult medulloblastoma, he underwent suboccipital craniotomy with gross total excision of the tumor. On histopathological examination, he was diagnosed with eGB. Cerebellar presentation of eGB is a rare event that has not been previously described in the literature. The present case also highlights the need for differentiating eGB from its morphological mimics by carefully interpreting histopathological and immunohistochemical examination findings.

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