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  Indian J Med Microbiol
 

Figure 2: Tubastatin A reduces the migratory potential of U87MG glioblastoma cells and demonstrates a synergistic effect with TMZ as a combination treatment (wound healing assay). (A) Images of the wound healing assay taken at different time points. Red bars show the migration front. (B) Analysis of the migrated area in each condition at different time points of the experiment. Data are presented as the mean ± SD from n = 3 independent samples assayed in triplicate. *P < 0.05, **P < 0.01, vs. control; #P < 0.05, vs. TMZ (one-way analysis of variance followed by Tukey's post hoc test). The experiment was repeated three times. Cyp: Cyclopamine, SD: Standard deviation, TMZ: Temozolomide, Tub A: Tubastatin A

Figure 2: Tubastatin A reduces the migratory potential of U87MG glioblastoma cells and demonstrates a synergistic effect with TMZ as a combination treatment (wound healing assay). (A) Images of the wound healing assay taken at different time points. Red bars show the migration front. (B) Analysis of the migrated area in each condition at different time points of the experiment. Data are presented as the mean ± SD from <i>n</i> = 3 independent samples assayed in triplicate. *<i>P</i> < 0.05, **<i>P</i> < 0.01, vs. control; <i>#P</i> < 0.05, vs. TMZ (one-way analysis of variance followed by Tukey's <i>post hoc</i> test). The experiment was repeated three times. Cyp: Cyclopamine, SD: Standard deviation, TMZ: Temozolomide, Tub A: Tubastatin A