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  Indian J Med Microbiol
 

Figure 4: Tubastatin A inhibits Sonic Hedgehog activation in U87MG glioblastoma cells. (A) Analysis of Gli1 expression by quantitative reverse transcription–polymerase chain reaction after tubastatin A treatment. Data are presented as means ± standard deviation from n = 3 independent samples assayed in triplicate. **P < 0.01, vs. control (Student's t-test). (B) Analysis of Sonic Hedgehog activity by luciferase assay after tubastatin A treatment. Data are presented as means ± standard deviation from n = 4 independent samples assayed in triplicate. *P < 0.05 (one-way analysis of variance followed by Tukey's post hoc test)

Figure 4:  Tubastatin A inhibits Sonic Hedgehog activation in U87MG glioblastoma cells. (A) Analysis of Gli1 expression by quantitative reverse transcription–polymerase chain reaction after tubastatin A treatment. Data are presented as means ± standard deviation from <i>n</i> = 3 independent samples assayed in triplicate. **<i>P</i> < 0.01, vs. control (Student's <i>t</i>-test). (B) Analysis of Sonic Hedgehog activity by luciferase assay after tubastatin A treatment. Data are presented as means ± standard deviation from <i>n</i> = 4 independent samples assayed in triplicate. *<i>P</i> < 0.05 (one-way analysis of variance followed by Tukey's <i>post hoc</i> test)